Морфологические изменения после лучевой терапии рака предстательной железы

В обзоре обобщены данные литературы последних десятилетий о морфологических изменениях ткани предстательной железы после лучевой терапии, включая дистанционное облучение и брахитерапию. Разобраны структурные, цитологические и иммуногистохимические изменения нормальной ткани и аденокарциномы, рассмотрены диагностические ловушки при оценке остаточной опухоли и особенности интерпретации суммы Глисона после облучения. Отдельное внимание уделено прогностическому значению контрольной биопсии, определению биохимического рецидива и феномену «скачка» уровня простатического специфического антигена после брахитерапии.

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